![]() ![]() Those who could, including most doctors, lawyers and merchants, fled the city. They were attracted by city streets filled with rubbish and waste, especially in the poorest areas. Rats carried the fleas that caused the plague. The death rate began to rise during the hot summer months and peaked in September when 7,165 Londoners died in one week. The earliest cases of disease occurred in the spring of 1665 in a parish outside the city walls called St Giles-in-the-Fields. Other parts of the country also suffered. While 68,596 deaths were recorded in the city, the true number was probably over 100,000. London lost roughly 15% of its population. ![]() or any other plague endemic area and have symptoms suggestive of plague, seek health care immediately.This was the worst outbreak of plague in England since the black death of 1348. If you live or have recently traveled to the western U.S. Preventive antibiotic therapy may also be given, depending on the type and timing of personal contact. People in close contact with very sick pneumonic plague patients may be evaluated and possibly placed under observation. The earlier a patient seeks medical care and receives treatment that is appropriate for plague, the better their chances are of a full recovery. Plague is a very serious illness, but is treatable with commonly available antibiotics. Once plague has been identified as a possible cause of the illness, appropriate treatment should begin immediately. Diagnosis is made by taking samples from the patient, especially blood or part of a swollen lymph gland, and submitting them for laboratory testing. In many cases, particularly in septicemic and pneumonic plague, there are no obvious signs that indicate plague. A known flea bite or the presence of a bubo may help a doctor to consider plague as a cause of the illness. The most common sign of bubonic plague is the rapid development of a swollen and painful lymph gland called a bubo. Plague is a plausible diagnosis for people who are sick and live in, or have recently traveled to, the western United States or any other plague-endemic area. Doctors examining a bubo caused by plague. ![]()
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